Solution Science for Research and Industry

Lifescience

16th Confocal Raman Imaging Symposium announced

Speakers from Germany, the USA and China will be at the 16th Confocal Raman Imaging Symposium being organised by our friends WITec in September.

Running from the 23rd to the 25th in Ulm, Germany, the symposium will cover aspects of modern Raman imaging and include a poster session detailing recent results in Raman imaging from various scientific fields.

An in-depth introduction to the operational principles and instrumental configurations relevant to confocal Raman microscopy will also be held at the equipment demonstrations.

During the three-day conference participants will be able to have in-depth discussions and networking opportunities with leading scientists and users of WITec microscope systems.

So, if you’re a scientist interested in chemically identifying and imaging samples at the highest spatial resolution, sign up here.

 

 


Iridian filters now available from Elliot Scientific

The Iridian range of filters for imaging, fluorescence, Raman and optical spectroscopy is now available in the UK and Ireland through Elliot Scientific.

Iridian-Banner-0

Scores of filters designed for bandpass – both short and long, edge pass, narrow notch and dichroic mirrors have been added to our website.

They are used in many spectroscopic investigations such as flow and emission cytometry, excitation and emission fluorescence, and more. Imaging filters for use in machine vision applications are available too.

We can also advise on custom filters for very specific scientific applications, and welcome OEM enquiries.

Please contact us for details, or visit our Iridian pages.


New patch clamp amplifiers from Tecella

Since 2007 Tecella has supplied electrophysiology measurement systems that allow pharmaceutical researchers to rapidly screen drugs and medical compounds thereby accelerating and improving drug discovery.

Tecella offer a range of instruments for this fundamental technique and have recently introduced the Flex and Impulse multiple channel models.

Flex – 8 to 96 channels

The Flex is a multi-channel patch clamp amplifier configurable from 8 to 96 channels in 8 channel steps.

It offers a comprehensive range of standard and customisable features:

Standard features

  • Voltage clamp
  • Low noise integrated digitiser
  • Internal head stage per channel
  • Internal model cell per channel
  • USB interface
  • TecellaLab software
  • USB powered for 16 channels or less

Custom features

  • Whole Cell, Bilayer, or Electrochemistry models
  • Current clamp
  • Command voltage range
  • Command current range
  • Gain values
  • Series resistance compensation range
  • Capacitance compensation

Impulse – 8 to 64 channel MEA amplifier

Impulse is a new compact and low noise 64-channel microelectrode array amplifier designed to work with a variety of probes. A Windows DLL is available for custom development and OEM integration.

For more information, please contact us.


Meet us at Focus on Microscopy 2019 from Sunday

The Focus on Microscopy (FOM2019) conference and exhibition begins this Sunday morning, April 14th, at the QEII Conference Centre in London, and runs for four long days.

FOM is an annual event that takes places in various countries around the world, presenting the latest innovations in optical microscopy and their application in biology, medicine and the material sciences. Topics will cover:

  • 3D optical imaging and image processing
  • Adaptive optics for microscopy
  • Coherent non-linear microscopies
  • Confocal and multiphoton-excitation microscopy
  • Correlated microscopies, light/electron
  • Developments in resolution and imaging
  • Fluorescence image, labelling and spectroscopy
  • Laser manipulation and tracking
  • Light sheet microscopy
  • OCT and holographic endoscopy
  • Phase/interference based microscopies
  • Raman spectroscopy imaging
  • Super-resolution nanoscopy
  • … and more

Elliot Scientific will be on stand 2 at the sold-out exhibition. We will be featuring Accurion active anti-vibration products; ultra-bright LED light sources from Prizmatix; and manipulators, stages and other microscopy accessories by Siskiyou.

Come and chat to us about our Optical Tweezer systems, digital holographic microscopes (DHM) from Lyncée Tec, and WITec confocal Raman imaging microscopes. We also offer Patch Clamp amplifiers manufactured by Tecella and the Kinetic Systems’ passive anti-vibration table and platform range, as well as HOLOEYE SLMs and CRAIC Technologies’ microanalysis systems.

For readers keen on acronyms and abbreviations, here a selection to get your teeth into: FCS, FLIM, FRAP, FRET, GSDIM, PALM, SHG, SIM, SOFI, STED, STORM, THG, and TIRF

 


April 2019 newsletter now online

April 2019 NewsletterThe Elliot Scientific April 2019 Newsletter: In this issue Gamma Scientific introduce a motorised iris for the RS-7 SpectralLED tuneable light source, Lake Shore manage to go low with calibrated Ruthenium Oxide temperature sensors for extreme cryogenic measurements, Siskiyou make mounts movable from above for those tricky optical breadboard set-ups, and we announce that our Applications section packed with useful information for scientists is now live, plus Focus on Microscopy 2019 in Westminster next week.

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March 2019 newsletter now online

March 2019 NewsletterThe Elliot Scientific March newsletter is now available. In this special life science issue we reveal how WITec’s new ParticleScout can help quickly identify and quantify, pollutants, unveil three new videos of products for microscopy and optogenetics from Prizmatix, announce that Siskiyou’s range of motorised manipulators are now available in the UK and Ireland, and show how Digital Holographic Microscopy from Lyncee Tec can help the research scientist, plus Magnetism 2019 in Leeds next month.

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Motorised Siskiyou micromanipulators for bioscience (and microelectronics)

For interaction with a microscope sample, the micromanipulator has been a staple of the biologists toolkit from the beginning of the 20th century.

Used for holding, injecting or cutting, the precision of the micromanipulator’s motion has always been paramount. So many leading researchers, including Dr Robert Chambers and Sir Andrew Huxley, worked on improving the mechanics of these systems over the years.

These early devices relied on adjustment of the individual axes by hand, but by the 1950’s De Fonbrune had developed a pneumatic micromanipulator that allowed all three axes to be operated via a joystick-like controller.

Depending on the application, researchers might need different movement ranges and resolutions, speeds and accuracy; so ranges of micromanipulators are available of different constructions to suit.

Siskiyou Corporation offer mechanical, hydraulic, and electronically-controlled motor adjusted systems.

The latter micromanipulators are fully CE-certified and are now on sale to UK and Irish researchers. Models available include:

MX1641 Series – ideal for introductory level research and training
This crossed roller micromanipulator uses spring-loaded lead screws on three axes to ensure drift-free operation, and a motorised probe axis delivering up to 0.1 µm movement resolution.

MX7600 Series – ideal for patch recording experiments
A fully motorised crossed roller bearing micromanipulator offering exceptionally smooth linear travel via its precision preloaded lead screws to ensure drift-free operation and up to 0.1 µm movement resolution.

MX7800 Series – ideal for multiple patch-recording experiments
This variant of MX7600 series uses a new folded Y-axis stage that narrows the footprint of the manipulator by half. This design enables the mounting of as many as six micromanipulators in a semi­circle from side to side around the front of a microscope.

For more information, please visit our Siskiyou Life Science Products, or contact us.

PS. Micromanipulators can also be useful for holding tools and probes while examining microelectronics under a microscope!

 


Using the most powerful single-chip LEDs available, Prizmatix LEDs are ideal for microscopy and optogenetics research

Prizmatix LEDs for Optogenetics and Fluorescence
  • High-power collimated and fibre-coupled LEDs
  • Wavelengths available from UV to Red
  • White Light and Multiple LED Sources

Prizmatix specialises in LED illumination systems for industrial applications, and science, especially in microscopy and optogenetics research.

The Prizmatix High Power and Ultra-High-Power (UHP) models are built using the most powerful single-chip LEDs available. These versatile illumination solutions offer:

Modularity
The modular systems deliver flexibility with a collimated beam. Fitted with a standard SM1 thread at the port, they can be fitted with a variety of accessories such as a fibre coupler adaptor, beam combiner, filter wheel, and more. The accessories are easy to fit and swap, so different set-ups only take minutes.

High efficiency
The fibre-coupled LED models have a highly efficient coupling that optimises the output such that these systems deliver roughly 1.5x more light when compared to Prizmatix LEDs used with a fibre adaptor. The LED controller is in-built to maximise its compactness.

Wide range of powers
High Power LED models are equipped with a 1 mm² single chip LED and can deliver up to 300 mW of optical power, while the UHP models have a 12 mm² single chip LED punching out up to 5 W of optical power. (As measured after the collimating optics)

Broad range of wavelengths
Choose from dozens of standard LEDs that operate at monochromatic wavelengths between 340 and 940 nm, and ‘white’ light models with a choice of spectral outputs. Deep UV and IR LEDs are also available on request.

Controls
Each of the extremely low-noise LED controllers has TTL and analogue input. In combination with a USB-control box, the LEDs can be controlled from a PC using µManager, LabView, Matlab or directly using HyperTerminal commands. An optional photodiode feedback loop enables the LEDs to be power stabilised.

Accessories
In addition to fibre coupling adaptors, collimators and filter wheels, custom-made fibres and fibre bundles with high numerical apertures of up to 0.63 are available. Optogenetics researchers can also order cannulae, rotary joints, and programmable signal generators for use in their experiments.

For more information, please visit our Prizmatix webpages or contact us.

 


February 2019 newsletter now online

February 2019 NewsletterThe Elliot Scientific February newsletter is now available. In this issue we go in deep with Lyncee Tec’s R-Series of Digital Holographic Microscopes, welcome the return of OptiBlocks from Prizmatix to our webpages, announce a training capability for spectroscopists interested in Raman Imaging from WITec, and recommend fiber optic components manufactured by market leader OZ Optics.

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We would like to say a big thank you…

We would like to say a big thank you to the people who visited our booth at Photonics West 2019 and met with Dr. Adrian Knowles in his new role as Elliot Scientific’s Managing Director. You certainly made it a successful event all round for both him and us.

Many visitors were impressed by our Elliot|Martock compact stage portfolio. These precision engineered dovetail slides are offered in a range of sizes and travels, delivering smooth backlash-free motion in X, XY, XZ, YZ or XYZ directions. Of particular interest to some were the miniature rotation stages.

Our Optical Tweezers demonstration videos are always attention grabbers, and a number of biophysicists and scientists from other disciplines stopped by to discuss how our cost-effective systems could help them in their projects. Researchers working within tight budgets were delighted to hear that Elliot Scientific laser trapping could be added to their existing (expensive) microscope without the need to buy a whole new instrument.

Elliot|Martock Gold Series Flexure Stages also proved of interest to many involved in light, optics and electronics due to their versatility. These world-renowned devices offer superior manipulation in three axes, and with minimal arcuate displacement they enable nanometre positioning for critical applications that include fiber launch and waveguide alignment. A comprehensive range of standard and customisable accessories are available too.

If you didn’t get to see us and our products at Photonics West, please visit our website or contact us for more information.

 

 


Photonics West opens today – Elliot Scientific in Booth 4660

The annual Photonics West group of exhibitions and conferences organised by SPIE – the international society for optics and photonics – opens today and runs till Thursday at San Francisco’s Moscone Center.

Elliot Scientific is exhibiting in Booth 4660 – look out for our banner (right) and new background (below).

 

We will be demonstrating our renowned range of XYZ flexure stages and precision micro- and nano-positioning slides, our fully automated DAli3 alignment system, as well as showing our Optical Tweezers add-on for professional microscopes.

More information can be found out about Photonics West 2019 here


January 2019 newsletter now online

January 2019 NewsletterThe Elliot Scientific January newsletter is now available. In this issue we say hello to Digital Holographic Microscopy specialists Lyncée Tec as we expand our life science range of products that currently come from Accurion, CRAIC Technologies, Elliot Scientific, HOLOEYE, Kinetic Systems, Prizmatix, Siskiyou, Tecella, and WITec. We also look at Lake Shore’s new M91 FastHall controller and remind you of next month’s Photonics West.

To view it in a browser, click here.

To read it magazine-style online, click here.

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